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Prenatal fluoride for nice teeth - by Ray Grogan
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Clinical trials of prenatal fluoride
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Clinical trials of prenatal fluoride

 

 

Lead author, journal , citation

Number of children in study

Age when checked

(years)

Percent reduction in tooth decay

Feltman

J Dent Med 1961 16(4):190-198

228

7

96%

Hoskova

Cesk Pediatr 1968 23:438-441

78

4

93%

Kailis

Med J Austral 1968 2:1037-1040

50

5

82%

Pritchard

Austral Dent J 1969 14:335-338

176

7

70%

Schutzmannsky

Dtsch Stomatol 1971 21:122-129

100

9

36%

 

Percent with no sign of tooth decay

Glenn 

Am J Obstet Gynecol 1982 143:560-64

117

5

97%

Leverett 

Caries Res 1997; 31:174-179

398

5

92%

Data from my favorite of the trials above:
 

Glenn FB, Glenn WD, Duncan RC. Fluoride tablet supplementation during pregnancy for caries immunity: A study of the offspring produced. Am J Obstet Gynecol 1982; 143:560-64. (Glenn was quick to tell me that many of these cases were a situation where the first child (the control) probably got poor care in pregnancy and at any rate was a basket case dentally when they took over for the pregnancy of the second child (the fluoride child) who probably got better care in pregnancy besides the fluoride. If nothing else the fluoride children went through pregnancy just as obstetricians realized that restricting the mothers weight was not a good idea. Also, the PNF children are younger and would not be expected to have as much tooth decay as their older sibs. But no matter how you correct the data, 97% caries free at age 5 years is still better than any other results with any other dose schedule.)

Groups

Dental data

Birth data

(both groups had F H2O)

No. sub

Age at dental exam yrs

DFS

Caries Free

Dent Defect

Wgt Lbs

Lngth inches

Pre-mature

C-Sec

Med Defect

PNF

117

5.2

.17

97%

0

7.6

20.3

1.9%

13.9%

0

Controls

375

9.0

8.7

15%

3

7.2

20.0

13.2%

13.6%

3

Dosage and sources